Pesquisa sobre: CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6 
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Descritor Inglês:   Cyclic Nucleotide Phosphodiesterases, Type 6 
Descritor Espanhol:   Fosfodiesterasas de Nucleótidos Cíclicos Tipo 6 
Descritor Português:   Nucleotídeo Cíclico Fosfodiesterase do Tipo 6 
Categoria:   D08.811.277.352.640.150.600
D08.811.277.352.640.155.750
D12.644.360.008.600
D12.644.360.009.750
D12.776.476.008.600
D12.776.476.009.750
Definição Inglês:   A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in the outer segment PHOTORECEPTOR CELLS of the RETINA. It is comprised of two catalytic subunits, referred to as alpha and beta, that form a dimer. In addition two regulatory subunits, referred to as gamma and delta, modulate the activity and localization of the enzyme. 
Nota Histórica Inglês:   2008(2001) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   52681 
Identificador Único:   D054707 

Ocorrência na BVS:
 

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